November 2015 | Case of the month - gain CPD points

History

A 54 year-old man was referred to clinic with a three month history of a rash that started on his right hand and spread up the forearm. The rash was non-tender and the patient was otherwise well.

There was no relevant personal or family history of skin problems.

The patient was on no medication.

He worked in an office-based job, and his main interest were tropical fish, having an aquarium at home.


Examination

Several, non-tender nodules on his right hand and forearm.


Investigations

What is the diagnosis?


Images

Diagnosis

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The diagnosis is mycobacterium marinum. 

Mycobacterium marinum is a non-tuberculous mycobacteria (syn. atypical mycobacteria).

The organisms primary habitat is fresh and salt water. In fresh water mycobacterium marinum prefers warmer water, especially if not replenished, with tropical fish tanks being a frequent source of infection.

As with this patient, the hands and forearms are the commonly affected sites if the infection is acquired from tropical fish tanks. The feet and lower legs are the predominant sites if the infection is acquired through swimming.

Mycobacterium marinum presents as a nodule or pustule, which may ulcerate. If untreated lesions often spread proximally.

Confirming a diagnosis of cutaneous tuberculosis can be very difficult - please refer to the chapter on Mycobacterial infections for further information on cutaneous mycobacterial infections, which includes notes on diagnostics.

Unlike other mycobacterial infections, treatment of mycobacterium marinum is relatively straightforward. Localised infection may be treated with 3-4 months of doxycycline or clarithromycin, in more troublesome cases rifampicin may need to be added in.

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