September 2016 | Case of the Month

History

A 56-year old uncircumcised man presented with a 12 month history of a red patch on his glans penis. The changes had come on gradually and were relatively asymptomatic. The symptoms had not responded at all to topical antifungal treatments and eumovate cream. There was no other skin history or genitourinary symptoms.


Examination

A red, glistening, moist-looking, erythematous patch on the glans penis.


Investigations

What is the diagnosis?


Images

Diagnosis

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The diagnosis is Zoon plasma cell balanitis.

Zoon plasma cell balanitis is a condition of the middle‐aged and older uncircumcised male. The condition is often asymptomatic and develops gradually. The classical clinical features consist of well‐demarcated, glistening, moist, bright red patches involving the glans and visceral prepuce, with sparing of the keratinised penile shaft and foreskin.

The main differential diagnosis is Erythroplasia of Queyrat (carcinoma-in-situ), which can have a similar appearance, usually a biopsy is needed to differentiate between the two.

Although Zoon balanitis can occasionally respond to improved self-care along with the use of moderate-potent topical corticosteroids, many cases persist, and the only proven cure is circumcision, although some claim that YAG or carbon dioxide laser treatment is effective.

Click here for more information on balanitis.

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